Product Details
Product Description
| Tosyl Chloride CAS 98-59-9 High-Purity Organic Synthesis Intermediate |
Product Name: Tosyl Chloride
CAS Number: 98-59-9
Molecular Formula: C7H7ClO2S
Molecular Weight: 190.65 g/mol
Chemical Name: p-Toluenesulfonyl chloride
EC Number: 202-684-8
p-Toluenesulfonyl chloride
Tosyl chloride
TsCl
4-Methylbenzenesulfonyl chloride
p-Methylbenzenesulfonyl chloride
Tosyl chloride, also known as p-toluenesulfonyl chloride, is an important organosulfur compound used widely in organic chemistry as a tosylating reagent. It appears as a white to slightly off-white crystalline solid with a pungent odor. Tosyl chloride is primarily used to convert alcohols into tosylates, which are excellent leaving groups for substitution and elimination reactions. This makes it indispensable in pharmaceutical synthesis, peptide coupling, and fine chemical production.
Tosylation of Alcohols and Amines – Transforms hydroxyl and amine groups into better leaving groups (tosylates) for further reaction.
Protecting Group – Used as a protective group for functional groups in multi-step synthesis processes.
Intermediate for Dyes and Agrochemicals – Key raw material for manufacturing advanced chemical intermediates.
API Intermediate – Widely used in the synthesis of active pharmaceutical ingredients (APIs).
Peptide Synthesis – Enables selective protection and activation of functional groups during peptide assembly.
Crosslinking Agent – Used in specialty polymer modifications and coatings.
Curing Agent – Plays a role in the formulation of thermosetting resins.
Reagent in Organic Laboratories – Common in research and development for testing synthetic routes and compound reactivity.
| Property | Specification |
|---|---|
| Appearance | White to off-white crystals |
| Purity | ≥ 99% (typically) |
| Melting Point | 65–70°C |
| Boiling Point | 136°C @ 15 mmHg |
| Solubility | Slightly soluble in water, soluble in organic solvents like dichloromethane, ether, benzene |
| Storage | Store in a cool, dry, ventilated place. Keep container tightly sealed. Protect from moisture. |
| Packaging | 25kg fiber drum / custom upon request |
Tosyl Chloride (CAS 98-59-9) is a highly efficient sulfonylating reagent used across the pharmaceutical, chemical, and research sectors. With its versatility, purity, and reactivity, it is an essential building block for many advanced chemical syntheses.
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